Cardiac Drugs- Rotation Prep

Hypertension Drugs

With Congestive Heart Failure:

ACE Inhibitors

Benazepril (Lotensin)

Enalapril (Vasotec) Lisinopril (Prinivil, Zestril)

Quinapril (Accupril)

In HF, ARBS may be combined with neprilysin inhibitor: Sacubitril

Beta blockers (Compensated HF)- contraindicated in cardiogenic shock

Atenolol (Tenormin)

Bisoprolol (Zebeta)

Nadolol (Corgard)

Nevibolol (Bystolic)

Propanolol (Inderal, InnoPran XL)

Aldosterone antagonists

Aldactone

CaroSpir

Eplerenone

Finerenone

Inspra

Thiazide Diuretics

Are used in osteoporosis since they hold on to calcium

With Diabetes:

ACE Inhibitors (protective against diabetic nephropathy)

ARBS

Calcium channel Blockers

Thiazide Diuretics

Beta Blockers

In Asthma:

ARBS, Calcium channel blockers, thiazide diuretics

Avoid ACE inhibitors to prevent confusion between drug or asthma related cough

Selective Beta- 1 blockers

In Pregnancy:

Hydralazine (Apresoline, BiDil)

Vasodilates arterioles > veins by increasing cGMP, causing smooth muscle relaxation. Reduces afterload

Co-administered with a Beta-Blocker to prevent reflex tachycardia

A/E: Fluid retention, angina, SLE-like syndrome, compensatory tachycardia

C/I in angina and Coronary artery disease

Labetalol (Trandate)

Methyldopa (Aldomet)

Nifedipine (Procardia)

Lipid Lowering Agents

Lipid Lowering Agents