Biochem:
Gaucher's disease
I-cell disease
Tay Sach's disease
Pompe's disease
MELAS
Collagen synthesis (hydroxylation of proline, diseases associated with primary, secondary and tertiary structures)
Wernicke Korsakoff
Loss of protein = methionine needed for protein synthesis
Pyruvate kinase deficiency and G6PD defi
Homocysteinuria
Lipoprotiens (APO C-2
Starvation state
Vitamin B3 is part of a cofactor (thiamine pyrophosphate) that contains adenine.
Vitamin B12 and Vitamin B9 difference (increased homocysteine in both but normal methylmalonic acid).
Effect of epinephrine on hypoglycemia: Stimulates hepatic glucose production
Fed state and fasting state enzymes
Morphine (how it causes deterioration)
Iron deficiency anemia lab findings
Glycogen phosphorylase deficiency
G - protein
Acid hydrolases found in lysosomes
Blotting
Genetics:
2 siblings have 1/4 chance of having identical HLA genes
Hardy Weingburg
Gluthathione reductase similar to G6PD
Modes of inheritance and probability
Heteroplasmy
Gonadal mosaism
Immuno:
Hypersensitivity (type 3)
GI
Intrinsic factor from parietal cells
Peutz Jeghers
MSK:
Bullous Pemphigoid and Pemphigus Vulgaris
Brachial plexus and Lumbar plexus
Brachial cyst
Osteosarcoma
NSAIDS
Cyclosporine
Tuberous sclerosis
Sciatica
Psoriasis
Fracture and dislocation of hand bones
Sarcomere (M line, A line and z line)
Chondrosarcoma
Rosacea
Apocrine glands (cause odor due to fat secretion)
Osteoid osteoma
Tennis elbow: inflammed extensor carpi radialis brevis
Gouty athritis
Actinic keratosis
Rotator cuff muscles
Dysplastic nevi
Metastasis: Bone into lung, Breast into pericardium, Prostate to bone, colon to liver, heart to brain, DVT to lung
Position for needle in thoracentesis at midaxillary line? 9th intercostal space
Flexor digitorum profundus damaged if we cannot flex the distal phalynges
CREST syndrome and Raynaud's phenomenon
Hereditary hemorrhagic telangiectasia.
Cell junctions, desmosomes, skin layers
Alendronate
Leucovorin
Gout
Cell cycle
GCSF
Probenecid
Muscles of mastication
Achondroplasia
Kidney stones
Paget's disease
Dermatomyositis
Neuro:
Myasthenia Gravis and Lambert Eaton Syndrome
Alcohol (formic acid,
Pediatric and Adult tumors: Pinealoma, Craniopharyngeoma, Glioblastoma
Neurotransmitters
Baclofen
Cranial nerve signs
Narcolepsy
Stimulation of certain receptors
Brain Hematomas: Epidural, subdural, subarachnoid
Parts of the cerebral hemisphere functions
Spinal cord lesions
Damage to Basal ganglia: Parkinson's, Hungtington's, Internal capsule
How Succinylcholine causes prolonged apnea
Eye circles diagram lesions
Entrapment of inferior rectus and inf oblique muscles occur in fractur of orbital floor
Rabies
Histo seen in brain in time periods after a stroke
Wernike Kossakoff syndrome
NMDA receptors
Multiple sclerosis
Shock
Schwanomma arises from neural crest cells
PICA and other brain stem lesions
Vitamin Deficiencies
PG
Dermatomes
Diuretics: acetazolamide, mannitol
Methamphetamine
Cholinergic drugs: especially succinylcholine, neostigmine, physostigmine, pheostigmine and atropine
Seizure treatments
The foreamens in the skull
Occlusion of Brain supply blood vessels
Relation between O2 and the brain (too much CO2 causes vasocontriction)
Repro:
Tamoxifen
Ovarian tumors
Steroids: suppression of GnRH
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